Adobe Reader/Acrobat 0-day Clarification - Secunia Blog

Disabling JavaScript does not prevent exploitation
Over the last couple of days, we have seen many sources recommend users to disable support for JavaScript in Adobe Reader/Acrobat to prevent exploitation. While this does prevent many of the currently seen exploits from successfully executing arbitrary code (as they rely on JavaScript), it does not protect against the actual vulnerability.

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関連
http://d.hatena.ne.jp/noushibou/20090220/1235116513